高尿酸血症是人体内尿酸生成与排泄稳态失衡的一种常见代谢性疾病,与痛风、肾结石、高血压等疾病密切相关。随着人们生活质量的提高和高嘌呤饮食的频繁摄入,高尿酸血症的发病率越来越高,发病年龄越来越低。目前对于高尿酸血症的临床治疗,西药大多具有严重的副作用和局限性,因此需要寻求有效、安全的替代治疗方法。大量研究发现中药在治疗高尿酸血症方面具有良好的疗效性和安全性。槲皮素因其天然的黄嘌呤氧化酶抑制特性而引起广泛研究,有关其降尿酸机制的研究已多次出现在相关文献和基础研究中,因此本文对其研究进行了系统综述。Hyperuricemia acid is a common metabolic disorder with imbalance of uric acid production and excretion. It is closely related to gout, kidney stones and hypertension. With the improvement of People’s quality of life and the frequent intake of high purine diet, the incidence of Hyperuricemia is higher and higher, and the age of onset is lower and lower. At present, Western medicine has serious side effects and limitations in the clinical treatment of Hyperuricemia, so it is necessary to seek effective and safe alternative therapies. A large number of studies have found that traditional Chinese medicine has good efficacy and safety in the treatment of Hyperuricemia. Quercetin is widely studied because of its natural Xanthine oxidase inhibitory properties. The mechanism of quercetin in reducing uric acid has appeared in the relevant literature and basic research many times, therefore, this paper makes a systematic review of its research.
