目的:探讨儿童与成人肢端黑素细胞痣的皮肤镜特征。方法:收集2020年7月至2023年7月儿童和成人肢端黑素细胞痣的皮肤镜资料,回顾性分析儿童与成人肢端黑素细胞痣皮肤镜特征的差异,与痣类型、病变部位的相关性,并观察研究了常见恶性黑素瘤皮肤镜特征在儿童与成人肢端黑素细胞痣中分布情况。结果:收集584例患者,共608处皮损,女性425处(69.9%),男性183处(30.1%),儿童组(P = 0.017)在足跖受压部位常见;而在成人组各皮肤镜模式未发现与部位有相关性,在不同部位中所占比例无统计学意义。在获得性黑素细胞痣中,儿童组各皮肤镜模式与部位无相关性;而在成人组与部位有相关性:网格样/网球模式(P P P P = 0.033),而在获得性黑素细胞痣中,仅在成人患者中观察到黑素瘤特殊皮肤镜结构。结论:儿童和成人肢端黑素细胞痣皮肤镜模式存在一定差异,与痣的类型及分布部位的相关性也不同,黑素细胞瘤皮肤镜结构中的皮嵴模式在儿童先天性黑素细胞痣中较成人多见,皮嵴模式对于儿童先天性黑素细胞痣与恶性黑素瘤鉴别诊断的特异性较低。掌握儿童与成人肢端黑素细胞痣皮肤镜特征的差异,对改善黑素细胞痣的临床管理具有重要意义,尤其可减少儿童患者不必要的切除。Objective: To investigate the dermoscopic features of acral melanocytic nevus in children and adults. Methods: Dermatoscopic data of acral melanocytic nevus in children and adults were collected from July 2020 to July 2023, and the differences in dermatoscopic features of acral melanocytic nevus in children and adults were retrospectively analyzed for their correlation with the type of nevus and the location of the lesion, and the distribution of dermatoscopic features of common malignant melanomas in acral melanocytic nevus of children and adults was studied observationally. Results: A total of 608 lesions were collected from 584 patients, 425 (69.9
